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The liver is the largest organ in the body located in the upper right part of the abdomen, below the diaphragm and above the stomach. It is responsible for many bodily functions, including the production and secretion of bile and the secretion of bilirubin, cholesterol, and hormones. It also helps activate enzymes. In addition, it metabolizes fats. And proteins and carbohydrates, so liver disease can lead to many complications that can disrupt many or all of these functions, and the worst part is that symptoms don’t occur until it’s too late, according to the Sada El Balad website.
There are different types of liver disease, but most liver disease develops the same way. The stages of liver disease can be divided into four stages:
Inflammation: Early in liver disease, the liver becomes inflamed and swollen. This is caused by the body’s natural response to infection. Sometimes an excess of toxins in the blood can also lead to hepatitis.
Fibrosis: If left untreated, hepatitis can lead to organ scarring, also known as fibrosis.
Cirrhosis: Cirrhosis is an irreversible condition characterized by severe scarring of the liver, characterized by cellular degeneration, inflammation and thickening of fibrous tissues.
Liver failure: Liver failure is the final or most severe stage of liver disease, when the liver completely stops working.
Most liver symptoms occur only during the most severe stages, which makes the disease very worrying and dangerous.
According to experts, one of the common signs in patients is deformed nails, while the specific reasons for these nail changes are unknown, but research conducted by the Department of Dermatology at Egyptian Sohag University confirms that ‘they can be the result of weak immunity. , iron deficiency or anemia blood or aging.
It is important for clinicians to understand and carefully examine the color, texture, thickness, and curvature of the nails to achieve a quick and early diagnosis of liver disease.
The Department of Dermatology at Sohag University confirms that “clumping of the fingers” is a common sign of chronic liver diseases, especially primary biliary cirrhosis and chronic active hepatitis.
Early findings suggest that clubbing caused by cirrhosis is not the result of bone disorders but rather the result of increased peripheral blood flow when the veins in the finger are dilated.
According to a 2010 Egyptian study, nail changes were reported in approximately 68% of patients with liver disease.
Another study found that a total of 80.5% of liver patients had nail changes, which is a higher prevalence than found in previous research.
Similarly, a 2013 study published in the journal Evolution of Medical and Dental Sciences recorded nail changes in 72% of patient samples.
According to the UK’s National Health Service (NHS), cirrhosis can take decades to develop and symptoms can appear in random order.
Yellowing of the skin and the whites of the eyes (jaundice)
He vomits blood
Easy bleeding or bruising
Swelling of the legs (edema) or abdomen (ascites) due to fluid buildup
How to prevent the development of cirrhosis?
Although there is currently no cure for cirrhosis, there are ways to control symptoms and complications and slow its progression, says the UK’s National Health Service (NHS).
According to the Mayo Clinic, patients with cirrhosis of the liver should avoid drinking alcohol or smoking. The health authority advises patients to eat healthy foods, preferably low sodium foods. counter medication carefully. .
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